Lois Ramondetta, MD
MD Anderson Cancer Center
Clinical Title: Targeting Stress Factors in Women with Advanced and /or Recurrent Cervical Cancer. Phase II study
The stress hormone noradrenaline fuels the growth and spread of aggressive malignant tumors. Previous studies suggest a new and potentially life-saving role for beta blockers, drugs commonly used to treat heart arrhythmias and high blood pressure. Beta blockers reverse the effects of noradrenaline. It is hypothesized that the use of a beta blocker propanolol and relaxation intervention down regulate the effects of neurobiological stressors in patients with advanced cervical cancer and thereby increase overall survival and progression free survival.
Status: Active Trial
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